Peroxides amagwiritsidwa ntchito mosiyanasiyana popanga organic synthesis, koma palinso zoopsa zazikulu zachitetezo, makamaka zosungunulira monga ether, tetrahydrofuran ndi isopropyl mowa, zomwe zimakhala zosavuta kupanga organic peroxides pakapita nthawi yayitali, ndipo ngati anyalanyazidwa pakugwiritsa ntchito, ndikosavuta kuphulika. Ndikofunika kupeza wodalirika, waponseponse komanso tcheru njira yodziwira ma organic peroxides pachitetezo cha labotale.
Mu 2020, Org.Process Res.Dev. (Org.Process Res.Dev. 2020, 24, 7, 1321-1327) adasindikiza njira yodziwira kuchuluka kwa ppm organic peroxides kutengera madzi chromatography-ultraviolet (LC-UV). Njirayi ndi yophweka komanso yovuta. Chitsulo chosinthira chinapangitsa kuti peroxides ndi sulfide apange ma sulfoxides. Zomwe zili mu sulfoxides zidatsimikiziridwa mwachindunji ndi kuzindikira kwa LC. Malire odziwika a sulfoxides adafika 1 μg/mL pogwiritsa ntchito mzere wamba wa C18 ndi chowunikira cha UV.
Kupyolera mu zoyesera, ofufuzawo adatsimikiza kuti pentavalent vanadium OV(OiPr)3 monga chothandizira, benzyl phenyl sulfide ngati gawo lapansi, LC kuti azindikire zomwe zili mu sulfoxide 3 chinali chophatikiza chabwino kwambiri, ndipo zomwe anachita zitha kumalizidwa mkati 4 maola. Ofufuzawa adagwiritsa ntchito njirayi pophunzira THF ndi MeTHF ndipo adapeza kuti:
1.BHT imatha kulepheretsa kupanga peroxide. Pa kuyesa kwa masabata asanu ndi limodzi, kaya yasungidwa mu nayitrogeni kapena mpweya, magalasi mandala kapena bulauni galasi, kuchuluka kwa peroxide kumakhala kochepa kuposa < 10 ppm;
- THF ndi MeTHF zopanda BHT zitha kusungidwa bwino mumlengalenga wa nayitrogeni;
- Pambuyo pokumana ndi mpweya m'mabotolo onse agalasi ofiirira komanso omveka bwino, peroxide zomwe zili mu THF ndi MeTHF zidawonjezeka, ndipo kuchuluka kwa peroxide mu MeTHF kunali kofulumira kuposa ku THF.
