Select Page


1, 1, 3, 3-Tetramethyl Guanidine

  • Product Name: 1, 1, 3, 3-Tetramethyl Guanidine
  • Other Names: TMG
  • Cas No.: 80-70-6
  • Purity: 99.90%
  • MF: C5H13N3
  • Appearance: Colorless transparent liquid
  • Package: Drum
  • Certificate: ISO
  • Application: This product is an important chemical raw material, which is used in the synthesis of headhold series antimicrobials in the pharmaceutical industry.
  • Sample: Available

Send Email To Us


7 + 14 =

Product Detail

Tetramethyl guanidine (TMG for short) is a strong organic base catalyst, which has a wide range of industrial applications, mainly used in the synthesis of new antibiotics cephalosporin cosolvent; It can also be used as a catalyst for polyurethane foam. It can also be used for the dyeing of nylon, wool and other proteins to improve their durability.

Product Parameter

Synonyms TMG
Chemical Formula C5H13N3 CAS Number 80-70-6
Molar mass 115.8
Appearance Colorless transparent liquid
Odor Slight smell
Density 0.918
Boiling point 160-162°C
Melting point -30 °C
Flash point 140 °F
Vapor pressure 0.2 mm Hg ( 20 °C)
Refractive index 1.4692
Quality standard Content ≥99% ; Moisture ≤0.2%
Solubility Acetonitrile (Slightly), DMSO (Slightly), Methanol (Slightly)
Solubility in water miscible
log P -0.49 at 20°C
Sensibility Air Sensitive
Stability Stable. Combustible. Incompatible with strong oxidizing agents, mineral and organic acids, carbon dioxide. Air-sensitive.
Quality standard Content ≥99% Moisture ≤0.2%
package 180kg/barrel (galvanized drum or plastic drum) ; 25kg/barrel (plastic drum)
Storage condition Store below +30°C.



1. Catalyst: tetramethylguanidine, as an alkaline compound, is commonly used as an intermediate of catalyst or base catalyst. It can be used to promote various organic reactions, such as oxidation reactions, esterification reactions and vinylation reactions.

2. Removal of oxidant: tetramethyl guanidine can be used as an oxidant removal agent, which can consume the active oxidant in the excess hydrogen peroxide, benzoyl peroxide and other oxidants, and reduce its oxidation reaction to the substance.

3. Dye intermediates: tetrmethyl guanidine has good reactivity and nucleophilicity, and can be used to synthesize dyes and dye intermediates. It can be used as a reagent to synthesize dyes and participate in the substitution reaction of nitrogen atoms in dye molecules.

4. Super base: Due to the strong alkali of tetramethylguanidine, it can be used as a super base in some fields. For example, it can be used to accelerate the formation of carbonates, the synthesis of polyamides, and the cyclization of polymers.

5. Electronic materials: chemical tetramethylguanidine has excellent polymerization performance and high melting point, which can be used for polymer synthesis in the field of electronic materials.

In addition, tetramethylguanidine has a number of other applications, such as synthetic drugs, as an ingredient in antibacterial agents and flame retardants.

Multiple uses of products

It use in Chemical Manufacturing,Polymer Industry,Plastics Industry,Rubber Industry,Textile Industry,Construction and Building Materials Industry